Scientists at the Institute of Genomics and Integrative Biology, in collaboration with Indraprastha Institute of Information Technology Delhi (IIIT-Delhi), have developed a rapid and sensitive method to detect Coronavirus infection within 30 minutes using a mass spectrometer.
The samples for the study were provided by National Centre for Disease Control, while Indraprastha Institute of Information Technology (IIIT-Delhi) took care of the computational work. The computational work that has been instrumental in bringing about this research has shown great potential and could turn out to be an invaluable in the fight against future diseases as well that haven’t been discovered yet.
The samples used in this research from the standard nasal and throat swab. The major challenge that was faced was to uniquely identify viral protein peptides that have no match to any human proteins and can be detected in the mass spectrometer.
Compared to other methods, the mass spectrometer based test doesn’t require hybridisation and/or amplification, which can potentially result in a few false negative results. The test is also comparatively much faster as well – delivering the results within 30 minutes.