As per a latest study, the most commonly prescribed classes of antibiotics may pose a risk to your heart. The study, published in the Journal of the American College of Cardiology, found that current users of fluoroquinolone antibiotics, such as Ciprofloxacin, face a 2.4 times greater risk of developing aortic and mitral regurgitation, where the blood backflows into the heart, compared to patients who take amoxicillin, a different type of antibiotic.
The greatest risk is within 30 days of use, according to the researchers at the University of British Columbia (UBC) in Canada.
Recent studies have also linked the same class of antibiotics to other heart problems, they said.
Some physicians favour fluoroquinolones over other antibiotics for their broad spectrum of antibacterial activity and high oral absorption, which is as effective as intravenous, or IV, treatment.
“You can send patients home with a once-a-day pill,” said Mahyar Etminan, an associate professor at UBC.
“This class of antibiotics is very convenient, but for the majority of cases, especially community-related infections, they’re not really needed. The inappropriate prescribing may cause both antibiotic resistance as well as serious heart problems,” said Etminan.
“This study highlights the need to be thoughtful when prescribing antibiotics, which can sometimes cause harm,” said Bruce Carleton, a research investigator at UBC Children’s Hospital.
Scientists analysed data from the US Food and Drug Administration’s adverse reporting system.
They also analysed a massive private insurance health claims database in the US that captures demographics, drug identification, dose prescribed and treatment duration.