According to study conducted at the University of North Carolina Health Care, automated ultraviolet devices can significantly reduce pathogens in hospital patient rooms.Researchers used an automated UV device, Tru-D, to decontaminate patient rooms contaminated with MRSA, vancomycin-resistant enterococcus, Clostridium difficile and a multi-drug resistant strain of Acinetobacter baumannii. During the first phase of the trial, samples of MRSA, vancomycin-resistant enterococcus, Acinetobacter baumannii, and Clostridium difficile were placed behind objects and within line-of-sight of the ultraviolet device. The findings revealed that the ultraviolet device reduced vegetative bacteria counts by more than 99.9% within 15 minutes. It also reduced the Clostridium difficile spore counts by 99.8% within 50 minutes. In the second phase of the trial, isolation rooms for patients with MRSA or vancomycin-resistant enterococcus were tested using the device. After 15 minutes of ultraviolet-device exposure, there was a significant decrease in the total number of colony-forming units (384 vs 19), positive MRSA samples (81 vs two) and MRSA counts per plate (37 vs two). Similar reductions were observed for vancomycin-resistant enterococcus.