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HIV-1 Undergoing Evolution

HIV-1 virus has been undergoing viral evolution in India over the past decade, the HIV-AIDS lab at Jawaharlal Nehru Centre for Advanced Scientific Research in Bangalore has found. Virus may be going through evolution possibly in other parts of the world as well, says the study conducted by the institute.

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The scientists found the emergence and expansion of three to five new strains of the Human Immunodeficiency Virus Type I rapidly replacing the standard viral strain, according to a press release on `Emergence and expansion of variant viral strains of HIV-1 in India and other global regions`.

The study is the first of its kind to identify that a major family of HIV-1 undergoing an evolutionary modification. The discovery from the study has been published in the Journal of Biological Chemistry by the group led by Prof Ranga Uday Kumar of Molecular Biology and Genetics Unit of JNCASR.

The YRG Centre for AIDS Research and Education (YRG CARE), Chennai, St. John`s National Academy of Health Sciences, Bangalore, National Institute of Mental Health and Neurological Sciences Bangalore, and the All India Institute of Medical Sciences, New Delhi took part in the research.

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Scientists from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, the USA also participated.

 

 

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