Dr Pavan Kumar informed, “It is the most refined fourth generation bio-prosthesis called “TRIFECTA VALVE” presently available among all tissue valves. With price tag of Rs. 2,50,000/- per piece, it is expensive but has latest technology incorporated in designing and manufacturing thus providing long lasting durability of 20 years and beyond as claimed by manufacturers.” He further adds, “This fourth generation prosthesis is probably best for heart patients. The latest trend is towards the use of biological (Tissue Heart Valve) valve similar to western world now, as patients demand drug free post-operative period.”

Trifecta Valve was introduced in India in February 2012 after two years of over 1200 implanta-tions all over the world. It is pericardial tissue valve placed on Titenum housing with latest Linx technique anti- calcification treatment for longer durability, providing best haemodynamic even in smallest size among all tissue heart valves.

With introduction of this valve, patients of heart valve disease especially beyond their fifties and ladies in child bearing age will have tremendous relief now. This Trifecta valve eliminates anti-coagulation treatment after implantation. This removes all side effects and consequent complications of anticoagulation treatment in long term for patients with mechanical heart valve prosthesis.

Facts suggest that presently among all heart diseases 35% to 40% patients suffer from heart valve disease. This is mainly due to post Rheumatic infection in childhood or by birth malforma-tions in valves. In elderly patients this can be degenerative disease of valve.
In India, more than 1,50,000 patients undergo heart valve operations of repair and replacement every year. This is usually considered as safe heart operation with mortality of less than 4% in experienced surgeons and good centres.

New features include:
• A companion image (from the original exposure) for pneumothorax visualization that accentuates the appearance of free air in the chest cavity. A new ICU package also in-cludes Tube and Line Visualization and automatic image display in the correct orientation for improved productivity and care.
• Pediatric image optimisation and enhancement software that expands and integrates a range of seven patient sizes as specified by new FDA regulations for pediatric exams. A new pediatric quality package also includes Carestream’s Total Quality Tool to verify image quality of CR cassettes as well as the system’s administrative analysis and reporting soft-ware.
• Vendor-neutral IEC exposure index values allow technologists to see if they are within the acceptable exposure range to improve overall workflow and image quality.
• Special image processing produces consistent rendering of portable chest images, which can reduce day-to-day and image-to-image variability, which is helpful to physicians who are monitoring changes in a patient’s condition.
• Enhanced Administrative and Analysis Reporting software provides a single, consoli-dated source for viewing all performance metrics for CR systems; and
• Multi-format print enhancements can help boost productivity with ability to add markers and adjust the image. Additional print layouts optimize film usage.

These compact DIRECTVIEW CR systems are designed for distributed and centralized CR appli-cations that require excellent image quality, rapid image availability, lower costs and high departmental productivity.

The scientists found that this ‘switch’ called Bruton’s tyrosine kinase (BTK) when turned on, activates the production of interferons – a potent class of virus killers that enables the body to fight harmful pa-thogens such as dengue and influenza viruses.
While there are anti-viral drugs to treat influenza, the high rates of mutation that are characteristic of the influenza virus have made it difficult to treat with one universal drug or vaccine. As for dengue, there are currently no clinically approved vaccines or cures either. This discovery of BTK’s role as a critical ‘switch’ that boosts the body’s anti-viral response, paves the way for developing anti-viral drugs that target the BTK ‘switch’ to fight infectious diseases.

To investigate the role of BTK in innate immunity, the research team from BTI extracted a class of in-nate immune cells known as macrophages from both normal mice and from mice deficient in BTK and challenged them with the dengue virus. They found that the BTK-deficient immune cells were unable to produce interferons, and hence had much higher viral counts compared to the healthy immune cells that had high-levels of interferons to fight the virus effectively.
To further demonstrate the critical role of BTK in anti-viral response, the team focused on BTK’s role in Toll-like Receptor 3 (TLR3) signalling. TLR3 is needed for cells to activate the interferon response when cells are infected by viruses. The team examined the effect of having a perpetually-“on” or -“off” BTK ‘switch’ in TLR3 signalling. They uncovered that a constitutively active or “on” BTK ‘switch’ enhanced the production of interferon, resulting in a stronger and more lasting anti-viral response with significant reduction in Dengue viral counts. In contrast, a perpetually “off” BTK ‘switch’ led to a poor anti-viral response with very low levels of inteferons produced, and little protection against Dengue virus infection.

Previously, scientists have always thought that BTK is important primarily in antibody production due to observations made of an inherited genetic disorder in humans called X-linked Agammaglobulinemia (XLA). These patients do not have a functional BTK ‘switch’, and are unable to produce antibodies because defects in BTK cripple maturation of B cells, a type of white blood cell that produces antibo-dies.

Diwakar Nigam, Newgen Software MD and CEO said “Newgen solutions have been implemented in 70 banks across 20 countries, in the EMEA region” He went on to add that, “Newgen BPM platform of-fers numerous possibilities, including Centralization of core processes and outsourcing of non-core processes enabling hundreds of processes to be automated on the same platform.”

Newgen received a tremendous response to its latest product innovation, ZapIn. The product is a mobile capture solution that helps business executive’s on-the-move to capture customer information in real time, at the point of customer contact and initiate its processing at the back-office. ZapIn is available both on Smart phones and Tablets.

Other prominent attendees of the customer meet included Abu Dhabi Commercial Bank, Dubai Bank, Bank Muscat, United Arab Bank, Bank Sohar, Central Bank of Bahrain, Arab National Bank, Standard Chartered Bank, Turkish Bank, Lloyds Bank, Mashreq Bank, Samba and First Gulf Bank.

Halal India is an independent Halal Certification body which is recognised by the Indian govern-ment and deals with certification of food, cosmetics and drugs as per the Shariah law.
The certification would mean they get ‘halal’ meat in food and have ‘quiblah’ (the direction of Mecca) signs in every room and prayer hall. Muslims offer prayers facing ‘quiblah.’ At least five leading hos-pital groups in India including Apollo Hospitals and Fortis are in talks with the authority, said Halal In-dia general manager Mohamed Noman Lateef.

Using the EnligHTN system, an ablation catheter delivers radio frequency (RF) energy to create lesions (tiny scars)along the renal sympathetic nerves – a network of nerves that help to regulate pressure; the intentional disruption of the nerve supply has been clinically found to decrease systolic blood pressure. This is important because the risk of cardiovascular death is cut in half with every 20 point decrease in systolic blood pressure.

The system is the industry’s first multi-electrode ablation technology for renal denervation.With the unique basket design, each placement of the ablation catheter allows a consistent and predictable pattern of four ablations in 90-second intervals.Compared to single electrode ablations, the multi-electrode EnligHTN system has the potential to improve consistency and procedural reliability, save time as well as result in workflow and cost efficiencies.Additionally,the minimal catheter repositioning may result in a reduction of contrast and fluoroscopic (x-ray) exposure.
The technology includes a guiding catheter, ablation catheter and ablation generator. The generator uses a proprietary, temperature-controlled algorithm to deliver effective therapy.