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Scientist finds non-invasive way to detect Inflammatory Bowel Disease

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inflammatory bowel diseaseChander Mohan, an Indian-American scientist has identified about 50 protein biomarkers that can non-invasively detect inflammatory bowel disease (IBD).

It is a disorder that leads to diarrhea, abdominal cramps, and weight loss.

He also received a $347,490 grant from the Crohn’s & Colitis Foundation of America.

IBD occurs when the body’s immune system fights its intestinal cells.

Two of the most common types are Crohn’s disease and ulcerative colitis, both of which lead to inflammation in the digestive tract.

It also leads to a variety of recurring symptoms such as diarrhea, abdominal cramps, blood in stools and weight loss.

“The disease is diagnosed by inserting an endoscope into the digestive tract to obtain a biopsy. However, this procedure does not lend itself to frequent disease monitoring or home-care tests,” said Mohan.

“To circumvent this, we asked if the stools from these patients might harbour specific molecules that we could potentially track,” he added.

Improved disease diagnosis, monitoring, and therapy in IBD can improve the lives of patients. Diagnosing or monitoring the disease from a stool test less invasive and cost-effective compared to endoscopy or colonoscopy.

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