The US Food and Drug Administration (FDA) has published a white paper on reducing the dose of radiation during imaging. The FDA initiative promotes safe use of medical imaging devices, supports informed clinical decision making and offers measures to increase patient awareness. decision making and offers measures to increase patient awareness. A radiation alert was issued when it was discovered that 206 patients who underwent CT perfusion studies in a hospital may have received 6 to 8 times more dose than what is necessary. Some patients suffer hair loss and reddening of the skin indicating high radiation doses. The Agency found out that the overexposures were more wide-spread. FDA has asserted that there must be appropriate justification for ordering and performing each procedure, and careful optimization of the radiation dose used.